Preoperative CT-based radiomics nomogram to predict the micropapillary pattern in lung adenocarcinoma of size 2 cm or less.

ABSTRACT:

Purpose

To develop and validate a radiomics nomogram model for predicting the micropapillary pattern (MPP) in lung adenocarcinoma (LUAD) tumors of ≤2 cm in size.

Methods

In this study, 300 LUAD patients from our institution were randomly divided into the training cohort (n = 210) and an internal validation cohort (n = 90) at a ratio of 7:3, besides, we selected 65 patients from another hospital as the external validation cohort. The region of interest of the tumor was delineated on the computed tomography (CT) images, and radiomics features were extracted. A nomogram model was established using radiomics features, clinical features and conventional radiographic features. The nomogram model was compared with the radiomics model and the clinical model alone to test its diagnos

SUBMITTER: Pan X 

PROVIDER: S-EPMC11752897 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature