Global leukemia burden and trends: a comprehensive analysis of temporal and spatial variations from 1990-2021 using GBD (Global Burden of Disease) data.

ABSTRACT:

Background

Leukemia, a group of malignant tumors, has been a significant public health concern due to its high incidence and mortality rates. This study aimed to provide an in-depth analysis of the global leukemia burden from 1990 to 2021 using the Global Burden of Disease (GBD) database, focusing on trends in incidence, mortality, and Disability-Adjusted Life Years (DALYs) across different regions, genders, and age groups including forecasting future trends.

Methods

Data were sourced from the GBD study, utilizing the Global Health Data Exchange (GHDx) query tool. We employed descriptive, trend, cluster, and forecasting analyses using age-standardized rates (ASRs) and the Estimated Annual Percentage Change (EAPC) to quantify changes over time. Hierarchical clustering and for

SUBMITTER: Huang P 

PROVIDER: S-EPMC11753064 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature