Multimodal treatments and the risk of breast cancer-related lymphedema: insights from a nationally representative cohort in South Korea.

ABSTRACT:

Background

As the roles of chemotherapy (Chemo) and radiation therapy (Radio) in the definitive treatment of breast cancer have expanded, a broader understanding of the factors associated with breast cancer-related lymphedema (BCRL) has become increasingly essential. Therefore, we investigated the association between multimodality treatment and the risk of BCRL.

Methods

In this retrospective study conducted using National Health Insurance data and the Korea National Cancer Incidence Database (2006-2017), 114,638 participants who underwent Surgery (Surg) or Chemo within 6 months after breast cancer diagnosis were enrolled, and the effect of multimodality treatment on the risk of BCRL was analyzed using the Cox proportional-hazards model. Multimodality treatment administered t

SUBMITTER: Jeong SH 

PROVIDER: S-EPMC11753110 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature