Potential roles of cigarette smoking on gut microbiota profile among Chinese men.

ABSTRACT:

Background

Cigarette smoking is posited as a potential factor in disrupting the balance of the human gut microbiota. However, existing studies with limited sample size have yielded inconclusive results.

Methods

Here, we assessed the association between cigarette smoking and gut microbial profile among Chinese males from four independent studies (N total = 3308). Both 16S rRNA and shotgun metagenomic sequencing methods were employed, covering 206 genera and 237 species. Microbial diversity and abundance were compared among non-smokers, current smokers, and former smokers.

Results

Actinomyces[g], Atopobium[g], Haemophilus[g], Turicibacter[g], and Lachnospira[g] were found to be associated with smoking status (current smokers vs. non-smokers). Metagenomic data provided a

SUBMITTER: Fan J 

PROVIDER: S-EPMC11753143 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature