Visceral fat area and subcutaneous fat area as measures of body composition in soft tissue sarcoma.

ABSTRACT:

Background and objectives

Soft tissue sarcomas (STS) are a heterogenous group of malignancies of mesenchymal origin. Given recent data linking obesity as well as the pattern of fat distribution with cancer outcomes, we sought to investigate the association of visceral fat area (VFA) and subcutaneous fat area (SFA) with oncologic outcomes in patients with STS undergoing surgery.

Methods

We analyzed data from 88 patients with STS diagnosed from 2008 to 2022. Predictor variables included body mass index (BMI), VFA, and SFA. VFA and SFA were obtained from computed tomography of the abdomen and pelvis. Univariable and multivariable Cox regression analysis was used to analyze associations between predictor variables and overall survival and recurrence-free survival.

Results

SUBMITTER: Garibay ER 

PROVIDER: S-EPMC11753180 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature