Epidemiology and outcomes of carbapenem-resistant <i>Klebsiella pneumoniae</i> infections in patients with hematological malignancies from 2014 to 2022.

ABSTRACT:

Background

We aimed to describe the epidemiology, cross-transmission, interventions, and outcomes of carbapenem-resistant Klebsiella pneumoniae (CRKP) infections in the hematological malignancies (HM) department of a hospital in China.

Methods

This prospective study was divided into three stages from 2014 to 2022: Period 1 (from 1 January 2014 to 4 March 2021), Period 2 (from 5 March 2021 to 31 December 2021), and Period 3 (from 1 January 2022 to 31 December 2022), with different measures implemented at each stage to evaluate the rate of new infections. The risk factors, epidemiological characteristics, data from all patients with CRKP, NGS gene sequencing molecular epidemiology analysis, and cross-transmission were described.

Results

A total of 217 patients wi

SUBMITTER: Li M 

PROVIDER: S-EPMC11753213 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature