Predictors of maternal-origin microchimerism in young women in the Philippines.

ABSTRACT:

Objectives

Microchimerism is the presence of a small quantity of cells or DNA from a genetically distinct individual. This phenomenon occurs with bidirectional maternal-fetal exchange during pregnancy. Microchimerism can persist for decades after delivery and have long-term health implications. However, little is known about why microchimerism is detectable at varying levels in different individuals. We examine the variability and the following potential determinants of maternal-origin microchimerism (MMc) in young women in the Philippines: gestational duration (in utero exposure to MMc), history of being breastfed (postpartum exposure to MMc), maternal telomere length (maternal cells' ability to replicate and persist), and participant's pregnancies in young adulthood (effect of ad

SUBMITTER: Pan TD 

PROVIDER: S-EPMC11753296 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature