Hybrid strains of enterotoxigenic/Shiga toxin-producing <i>Escherichia coli</i>, United Kingdom, 2014-2023.

ABSTRACT: Introduction. Diarrhoeagenic Escherichia coli (DEC) pathotypes are defined by genes located on mobile genetic elements, and more than one definitive pathogenicity gene may be present in the same strain. In August 2022, UK Health Security Agency (UKHSA) surveillance systems detected an outbreak of hybrid Shiga toxin-producing E. coli/enterotoxigenic E. coli (STEC-ETEC) serotype O101:H33 harbouring both Shiga toxin (stx) and heat-stable toxin (st).Gap statement. These hybrid strains of DEC are a public health concern, as they are often associated with enhanced pathogenicity. However, little is known about their epidemiology, clinical significance and associated public health burden.Aim. The aim of this study was to describe the microbio

SUBMITTER: Rodwell EV 

PROVIDER: S-EPMC11753528 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature