A double dissociation between semantic and spatial cognition in visual to default network pathways.

ABSTRACT: Processing pathways between sensory and default mode network (DMN) regions support recognition, navigation, and memory but their organisation is not well understood. We show that functional subdivisions of visual cortex and DMN sit at opposing ends of parallel streams of information processing that support visually mediated semantic and spatial cognition, providing convergent evidence from univariate and multivariate task responses, intrinsic functional and structural connectivity. Participants learned virtual environments consisting of buildings populated with objects, drawn from either a single semantic category or multiple categories. Later, they made semantic and spatial context decisions about these objects and buildings during functional magnetic resonance imaging. A lateral ventral

SUBMITTER: Gonzalez Alam TRJ 

PROVIDER: S-EPMC11753780 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature