Development of a Modular, Open-Source, Reduced-Pressure, Drift Tube Ion Mobility Spectrometer.

ABSTRACT: Toward the goal of minimizing construction costs while maintaining high performance, a new, reduced-pressure, drift tube ion mobility system is coupled with an ion trap mass analyzer through a custom ion shuttle. The availability of reduced-pressure ion mobility systems remains limited due to comparatively expensive commercial options and limited shared design features in the open literature. This report details the complete design and benchmarking characteristics of a reduced-pressure ion mobility system. The system is constructed from FR4 PCB electrodes and encased in a PTFE vacuum enclosure with custom torque-tightened couplers to utilize standard KF40 bulkheads. The PTFE enclosure directly minimizes the overall system expenses, and the implementation of threaded brass inserts allows fo

SUBMITTER: Buzitis NW 

PROVIDER: S-EPMC11753826 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature