Allergen sensitization patterns: Allergic rhinitis with multimorbidity versus alone-A real-world study.

ABSTRACT:

Background

Allergic rhinitis (AR) multimorbidity may need to be considered a specific disease because of distinct clinical and immunological differences from AR alone. Allergic multimorbidity often involves polysensitization, where allergen-specific immunoglobulin E (IgE) plays a significant role.

Objective

This study aims to explore differences in allergen IgE sensitization patterns between AR alone and AR multimorbidity.

Methods

A real-world case-control study was conducted with patients diagnosed with AR. Multivariate logistic regression analyzed the associations between AR multimorbidity and allergen sensitivity, allergen-specific IgE levels, and the count of positive allergens.

Results

A cohort of 2275 patients with AR was included, of which 1100 (48.4%) p

SUBMITTER: Li YT 

PROVIDER: S-EPMC11753898 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature