Assessment of heart rate deceleration capacity, heart rate deceleration runs, heart rate acceleration capacity, and lipoprotein-related phospholipase A2 as predictors in individuals with dementia.

ABSTRACT:

Background

Autonomic dysfunction plays an essential role in dementia, however, it is not known whether electrocardiogram autonomic dysfunction-related indicators are associated with the severity of dementia. In this study, we attempted to investigate whether these indicators are correlated in patients with vascular dementia and Alzheimer's disease compared with normal health individuals. For this purpose, we measured and analyzed the predictive value of heart rate deceleration capacity (DC), heart rate deceleration runs (DRs), heart rate acceleration capacity (AC) along with the plasma levels of lipoprotein-associated phospholipase A2 (Lp-PLA2).

Methods

We compared 83 dementia cases including 41 vascular dementia (VD), 42 Alzheimer's disease (AD) patients with 42 elderly hea

SUBMITTER: Wang Y 

PROVIDER: S-EPMC11754063 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature