Advancements in genetic research by the Hispanic Community Health Study/Study of Latinos: A 10-year retrospective review.

ABSTRACT: The Hispanic Community Health Study/Study of Latinos (HCHS/SOL) is a multicenter, longitudinal cohort study designed to evaluate environmental, lifestyle, and genetic risk factors as they relate to cardiometabolic and other chronic diseases among Hispanic/Latino populations in the United States. Since the study's inception in 2008, as a result of the study's robust genetic measures, HCHS/SOL has facilitated major contributions to the field of genetic research. This 10-year retrospective review highlights the major findings for genotype-phenotype relationships and advancements in statistical methods owing to the HCHS/SOL. Furthermore, we discuss the ethical and societal challenges of genetic research, especially among Hispanic/Latino adults in the United States. Continued genetic research,

SUBMITTER: Rao H 

PROVIDER: S-EPMC11754138 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature