Injecting hope: the potential of intratumoral immunotherapy for locally advanced and metastatic cancer.

ABSTRACT: Despite enormous progress, advanced cancers are still one of the most serious medical problems in current society. Although various agents and therapeutic strategies with anticancer activity are known and used, they often fail to achieve satisfactory long-term patient outcomes and survival. Recently, immunotherapy has shown success in patients by harnessing important interactions between the immune system and cancer. However, many of these therapies lead to frequent side effects when administered systemically, prompting treatment modifications or discontinuation or, in severe cases, fatalities. New therapeutic approaches like intratumoral immunotherapy, characterized by reduced side effects, cost, and systemic toxicity, offer promising prospects for future applications in clinical oncology

SUBMITTER: Skalickova M 

PROVIDER: S-EPMC11754201 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature