Population-based active surveillance of pertussis hospitalization rates in two cities of China.

ABSTRACT:

Purpose

Hospitalization is most common for severe pertussis cases and those with serious complications caused by pertussis. In mainland China, the immunization program consists of primary vaccinations at 3, 4, and 5 months, followed by a booster at 18 months with DTaP. It remains uncertain whether the first dose at 3 months, rather than 6 weeks as WHO recommended, may increase disease burden, as delayed immunization may lead to lagged protection. This study aimed to determine pertussis hospitalization rates by active surveillance in China, shedding light on immunization strategies for better disease control.

Methods

From June 1, 2021, to May 31, 2022, two Chinese cities underwent a population-based active surveillance. Suspected pertussis cases were confirmed as pertussis ca

SUBMITTER: Dai H 

PROVIDER: S-EPMC11754310 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature