Autologous platelet concentrates as adjuncts to non-surgical periodontal therapy: a systematic review and meta-analysis.

ABSTRACT:

Objective

To evaluate the possible additional clinical benefit from autologous platelet concentrate (APC) treatment adjunct to non-surgical periodontal therapy (NSPT).

Methods

Electronic (MEDLINE/Embase/Cochrane/MedNar/CORE) and hand searches were conducted. Following studies selection, evidence tables were formed, and meta-analyses were performed for the following outcomes: probing pocket depth (PPD) reduction, clinical attachment level (CAL) gain, and bleeding on probing (BoP) reduction. The protocol for this systematic review was registered in PROSPERO (CRD42023514388).

Results

After de-duplication, the initial search yielded 194 citations, from which ten papers were eligible for quantitative synthesis. The APC group comprised 270 patients, while the control group

SUBMITTER: Lipovec T 

PROVIDER: S-EPMC11754314 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature