Multi-omics approaches to deciphering complex pathological mechanisms of migraine: a systematic review.

ABSTRACT:

Background

Migraine represents a chronic neurological disorder characterized by high prevalence, substantial disability rates, and significant economic burden. Its pathogenesis is complex, and there is currently no cure. The rapid progress in multi-omics technologies has provided new tools to uncover the intricate pathological mechanisms underlying migraine. This systematic review aims to synthesize the findings of multi-omics studies on migraine to further elucidate the complex mechanisms of disease onset, thereby laying a scientific foundation for identifying new therapeutic targets.

Methods

We conducted a comprehensive systematic review, specifically focusing on clinical observational studies that investigate various aspects of migraine through the integration of genomics

SUBMITTER: Liu J 

PROVIDER: S-EPMC11754399 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature