A legume-enriched diet improves metabolic health in prediabetes mediated through gut microbiome: a randomized controlled trial.

ABSTRACT: Healthy dietary patterns rich in legumes can improve metabolic health, although their additional benefits in conjunction with calorie restriction have not been well-established. We investigated effects of a calorie-restricted, legume-enriched, multicomponent intervention diet compared with a calorie-restricted control diet in 127 Chinese prediabetes participants, living in Singapore. The study was a 16-week, single-blind, parallel-design, randomized controlled trial (n = 63 intervention group (IG), n = 64 control group (CG); mean ± SD age 62.2 ± 6.3 years, BMI 23.8 ± 2.6 kg/m²). Primary outcomes were markers of glycemia and all measurements were taken at 2 or 4-weekly intervals. At the end of 16 weeks, both groups had significantly lower BMI (q_(Time) = 1.92 ×10^-4

SUBMITTER: Wu X 

PROVIDER: S-EPMC11754483 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature