Associations of Retinal Microvascular Density and Fractal Dimension with Glaucoma: A Prospective Study from UK Biobank.

ABSTRACT:

Objective

To explore the association between retinal microvascular parameters and glaucoma.

Design

Prospective study.

Subjects

The UK Biobank subjects with fundus images and without a history of glaucoma.

Methods

We employed the Retina-based Microvascular Health Assessment System to utilize the noninvasive nature of fundus photography and quantify retinal microvascular parameters including retinal vascular skeleton density (VSD) and fractal dimension (FD). We also utilized propensity score matching (PSM) to pair individuals with glaucoma and healthy controls. Propensity score matching was implemented via a logistic regression model with a caliper of 0.1 and a matching ratio of 1:4 no replacements. We conducted univariable Cox regression analyses to study the as

SUBMITTER: Chen Q 

PROVIDER: S-EPMC11754513 | biostudies-literature | 2025 Mar-Apr

REPOSITORIES: biostudies-literature