Sequence-Based Multi Ancestry Association Study Reveals the Polygenic Architecture of Varroa destructor Resistance in the Honeybee Apis mellifera.

ABSTRACT: Honeybees, Apis mellifera, have experienced the full impacts of globalisation, including the recent invasion by the parasitic mite Varroa destructor, now one of the main causes of colony losses worldwide. The strong selection pressure it exerts has led some colonies to develop defence strategies conferring some degree of resistance to the parasite. Assuming these traits are partly heritable, selective breeding of naturally resistant bees could be a sustainable strategy for fighting infestations. To characterise the genetic determinism of varroa resistance, we conducted the largest genome wide association study performed to date on whole genome sequencing of more than 1500 colonies on multiple phenotypes linked to varroa resistance of honeybees. To take into account some genetic diversity o

SUBMITTER: Eynard SE 

PROVIDER: S-EPMC11754705 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature