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Review: Efficacy of preventative interventions for children and adolescents at clinical high risk of psychosis - a systematic review and meta-analysis of intervention studies.


ABSTRACT:

Background

Despite evidence suggesting that age moderates the response to preventative treatment for those at clinical high risk of psychosis (CHR-P), no meta-analysis has assessed the effectiveness of preventative interventions for CHR-P children and adolescents. Our aim was to synthesise evidence assessing preventative interventions on a wide range of mental health outcomes for CHR-P children and adolescents.

Method

A systematic search was conducted on Ovid MEDLINE, Pubmed, APA PsycInfo and Web of Science until June 2024 (PROSPERO: CRD42023406696). Intervention studies that had a mean participant age of under 18 years old that reported on mental health outcomes for CHR-P participants were selected. A meta-analysis was conducted for independent studies reporting the effecti

SUBMITTER: Frearson G 

PROVIDER: S-EPMC11754713 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature