The association between serum albumin levels and metabolic syndrome based on the NHANES and two sample Mendelian randomization study.

ABSTRACT: Previous studies have shown that serum albumin levels are associated with a greater risk of metabolic syndrome (MetS). However, it is unclear whether this association is causal or only influenced by confounding factors, so further investigation is needed to determine the causal relationships. Researchers selected participants with serum albumin, metabolic syndrome, and related covariates from the National Health and Nutrition Examination Survey (NHANES) database for a total of 14,036 individuals, including 5483 individuals with MetS and 8553 individuals without MetS. The association of serum albumin levels with metabolic syndrome and its components was estimated using weighted multivariable logistic regression, with its nonlinearity being examined by restricted cubic spline (RCS) regressio

SUBMITTER: Tang Y 

PROVIDER: S-EPMC11754745 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature