Field switching of microfabricated metamagnetic FeRh MRI contrast agents.

ABSTRACT: In a step towards generating switchable MRI cellular labels, we demonstrate in-situ field switching of micron scale metamagnetic Iron-Rhodium (FeRh) thin film particles. A thin-film (200 nm) FeRh sample was fabricated and patterned into an array of progressively smaller squares with sizes ranging from 500 μm down to 1 μm. The large first order phase change from antiferromagnetic to ferromagnetic state was characterized using vibrating sample magnetometry, magnetic force microscopy, and MRI. Room temperature MRI experiments sensitive to the local magnetic field surrounding the particles demonstrated the low moment state (OFF MRI contrast) at 4.7T and high moment state (ON MRI contrast) at 11.7T for the array where sizes down to 2-3 μm were observed in MRI at 50 μm resolution. The expected t

SUBMITTER: Dodd S 

PROVIDER: S-EPMC11754896 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature