Duration of Disease and Long-Term Outcomes in Patients With Difficult-To-Treat Recurrent Pericarditis: A Chronic Condition Treated With Nonsteroidal Anti-Inflammatory Drugs, Colchicine, Corticosteroids, and Anti-Interleukin-1 Agents.

ABSTRACT:

Objective

We aimed to investigate the remission rate and disease duration in idiopathic or post-cardiac injury pericarditis and risk factors for disease duration and anti-interleukin-1 (IL-1) agent discontinuation.

Methods

This was a multicenter, longitudinal, observational study including 370 patients (51.4% female). The remission rate was the proportion of patients who stopped all pericarditis-related therapies for at least 6 months without recurrences.

Results

The median follow-up was 4.9 (interquartile range [IQR] 2.8-8.4) years, and the median age at the end of follow-up was 49 (IQR 37-60) years. A median of 1.1 (IQR 0.6-1.9) recurrences/year and 0.4 (IQR 0.1-0.9) hospitalizations/year were recorded. The remission rate at follow-up was 34.0%, 7% per year. Disease

SUBMITTER: Ceriani E 

PROVIDER: S-EPMC11755118 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature