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Association of Depression Onset and Treatment With Blood Pressure Control After Intracerebral Hemorrhage.


ABSTRACT:

Background

Blood pressure (BP) control represents a crucial intervention to improve long-term outcomes following spontaneous intracerebral hemorrhage (ICH). However, fewer than half of ICH survivors achieve target treatment goals. ICH survivors are also at very high risk for poststroke depression, which may contribute to inadequate BP control. We, therefore, sought to determine whether depressive symptoms after ICH are associated with inadequate BP control. We also investigated whether associations between depression after ICH and BP measurements were mediated by treatment with selective serotonin reuptake inhibitors or norepinephrine-serotonin reuptake inhibitors antidepressants.

Methods

We leveraged data from a single-center longitudinal study of ICH conducted at Massachus

SUBMITTER: Keins S 

PROVIDER: S-EPMC11755381 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature