Age-specific abnormal glucose metabolism in HIV-positive people on antiviral therapy in China: a multicenter case-control study.

ABSTRACT:

Background

Update, the link between HIV infection and abnormal glucose metabolism (AGM) is still unclear. This study aims to investigate the impact of HIV infection on AGM, including insulin resistance (IR), impaired fasting glucose (IFG), and diabetes mellitus (DM).

Methods

A multicenter case-control study was conducted in Zhejiang province, China. After matching, the study included 1030 people living with HIV (PLWH) and 1030 people living without HIV (PLWTH). The age-specific incidence of AGM was compared between the two groups. Poisson regression models were used to calculate the relative risk (RR) and its 95% confidence interval (CI) to assess the associations.

Results

Compared to PLWTH, PLWH had a higher rate of IR, IFG and DM, and a higher risk of developing IR

SUBMITTER: Xu L 

PROVIDER: S-EPMC11755731 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature