Clinical course and potential associated factors of progressive calcinosis cutis in early systemic sclerosis: a cohort study.

ABSTRACT:

Background

Calcinosis cutis of hands can progress and impair hand function in systemic sclerosis (SSc). Understanding the natural disease and comprehensive management is crucial.

Objective

To examine clinical course and identify risk factors associated with progressive calcinosis cutis in early SSc.

Methods

Dual time-point hand radiography was performed at initial and after diagnosis at median interval (range 2.9 ± 0.4 years) in 53 recruited patients with early SSc. Progressive calcinosis cutis defined as the worsening of severity according to simple soring scoring system (no, mild, moderate, severe) comparing to previous hand radiography. Odds ratio (OR) and their 95%CI were used to evaluate associated factors and calcinosis cutis progression.

Results

A total

SUBMITTER: Kanjanajarurat V 

PROVIDER: S-EPMC11755737 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature