An exploratory study on the differential diagnostic indicators between adult systemic EBV-positive T-cell lymphoproliferative disorders and angioimmunoblastic T-cell lymphoma with multiple EBV infections.

ABSTRACT:

Background

The differential diagnosis between adult systemic EBV-positive T-cell lymphoproliferative disorders (EBV⁺ T-LPD) and angioimmunoblastic T-cell lymphoma (AITL) with multiple EBV infections is difficult, and distinguishing between the two has become a diagnostic challenge for pathologists. Given that the clinical treatment plans are different, an accurate diagnosis is a prerequisite to ensure effective treatment, therefore, it is extremely necessary and meaningful to find effective pathological indicators for distinguishing between two diseases.

Methods

We present a retrospective study comparing 7 cases of adult EBV⁺ T-LPD and 16 cases of AITL with multiple EBV infections diagnosed at our institution from 2017 to 2022. Differences in immunophen

SUBMITTER: Zheng X 

PROVIDER: S-EPMC11756112 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature