Prognostic Factors and Nomogram for Malignant Brainstem Ependymoma: A Population-Based Retrospective Surveillance, Epidemiology, and End Results Database Analysis.

ABSTRACT:

Purpose

This study aimed to identify prognostic factors and develop a nomogram for survival in patients with brainstem ependymoma.

Methods

Data of 652 patients diagnosed with brainstem ependymoma extracted from the Surveillance, Epidemiology, and End Results (SEER) registry from 2000 to 2020 were analyzed. Univariate and multivariable Cox regression analyses were performed to examine factors influencing overall survival (OS). Receiver operating characteristic curve (ROC) and calibration curves were used to verify the nomogram. The Kaplan-Meier method was used to analyze OS based on treatment methods stratification or different age patterns.

Results

Six independent prognostic factors of patients with brainstem ependymoma were identified, including age, race, marital st

SUBMITTER: Ji X 

PROVIDER: S-EPMC11756553 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature