First-year dynamics of the anaerobic microbiome and archaeome in infants' oral and gastrointestinal systems.

ABSTRACT: Recent research provides new insights into the early establishment of the infant gut microbiome, emphasizing the influence of breastfeeding on the development of gastrointestinal microbiomes. In our study, we longitudinally examined the taxonomic and functional dynamics of the oral and gastrointestinal tract (GIT) microbiomes of healthy infants (n = 30) in their first year, focusing on the often-over-looked aspects, the development of archaeal and anaerobic microbiomes. Breastfed (BF) infants exhibit a more defined transitional phase in their oral microbiome compared to non-breastfed (NBF) infants, marked by a decrease in Streptococcus and the emergence of anaerobic genera such as Granulicatella. This phase, characterized by increased alpha-diversity and significant ch

SUBMITTER: Neumann CJ 

PROVIDER: S-EPMC11756582 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature