Hormones, Stress, and Heart Disease in Transgender Women with HIV in LITE Plus.

ABSTRACT:

Introduction

Cardiovascular disease (CVD) is a leading cause of death among transgender women and people with HIV. Exogenous estrogen and psychosocial stressors are known risk factors for CVD. Yet, few studies have used biomarkers to examine the role of stress in CVD risk among transgender women with HIV (TWHIV). This analysis examined whether stress moderates relationships between gender-affirming hormone therapy (GAHT) duration and CVD risk among TWHIV.

Methods

This cross-sectional analysis of baseline data from an observational cohort of 108 Black and Latina TWHIV in Boston, New York, and Washington, DC, enrolled December 2020 to June 2022, measured sociodemographics, medical diagnoses, medications, smoking history, and perceived stress via interviewer-administered survey

SUBMITTER: Poteat TC 

PROVIDER: S-EPMC11757083 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature