Association between the triglyceride/high-density lipoprotein (TG/HDL) ratio and incidence of gout: A nationwide cohort study.

ABSTRACT:

Introduction

The global burden of gout, a severe and painful arthralgia, is of note and is expected to increase in the future. We aimed to investigate the association between the triglyceride/high-density lipoprotein (TG/HDL) ratio, a simple and validated biomarker for insulin resistance, and the incidence of gout in a longitudinal setting in the general population.

Methods

Our study was conducted using the National Health Insurance Service-Health Screening Cohort database of Republic of Korea (2002-2019). We included 300,107 participants who had no previous history of gout and had data for more than three repeated measurements of the triglyceride-glucose (TyG) index. The incidence of gout was determined using at least two or more claims of the ICD-10 code M10.

Results

SUBMITTER: Chang Y 

PROVIDER: S-EPMC11757121 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature