Recommendations for assessing commutability of a replacement batch of a secondary calibrator certified reference material.

ABSTRACT: Commutable secondary certified reference materials (CRMs) play an essential role in the calibration hierarchy of many in-vitro diagnostic measurement procedures used in the medical laboratory. Therefore, sustainable availability of these CRMs is crucial to guarantee the long-term equivalence of results obtained for the clinical samples. The IFCC Working Group on Commutability in Metrological Traceability (WG-CMT) has published several recommendations for assessing the commutability of secondary calibrator CRMs. Performing a full commutability study according to these recommendations may present significant demands on the resources of CRM producers. This report provides recommendations for performing commutability equivalence assessments between existing CRMs of proven commutability and rep

SUBMITTER: Deprez L 

PROVIDER: S-EPMC11757154 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature