The direct and urinary electrolyte-mediated effects of ambient temperature on population blood pressure: A causal mediation analysis.

ABSTRACT: High ambient heat can directly influence blood pressure (BP) through the vasodilation of the skin vasculature and indirectly by affecting urinary volume and electrolyte levels. We evaluated the direct and urine electrolyte-mediated effects of ambient temperature on BP. We pooled 5,624 person-visit data from a community-based stepped-wedge randomized control trial in southwest coastal Bangladesh from December 2016 to May 2017. Same-day ambient temperature data from local weather stations were linked to participant BP and urine electrolytes using geo-locations of their residential addresses. We implemented causal mediation analyses using the product methods of coefficients with linear mixed models under the sequential ignorability assumption. Separate models were run for each urinary electro

SUBMITTER: Mukhopadhyay A 

PROVIDER: S-EPMC11757155 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature