Feasibility and effects of cognitive training on cognition and psychosocial function in Huntington's disease: a randomised pilot trial.

ABSTRACT:

Background

Huntington's disease (HD) is a rare neurodegenerative disease that causes progressive cognitive, physical, and psychiatric symptoms. Computerised cognitive training (CCT) is a novel intervention that aims to improve and maintain cognitive functions through repeated practice. The effects of CCT have yet to be established in HD. This randomised pilot trial examined the feasibility of a large scale trial to assess efficacy of multidomain CCT in pre-manifest and early-stage HD.

Methods

28 participants were randomised to either at-home CCT (2 × 60 min sessions per week for 12 weeks; n = 13) or lifestyle education through monthly newsletters (n = 15). Participants completed cognitive tasks and questionnaires at baseline and follow up, either in person (n = 18) or via vi

SUBMITTER: Huynh K 

PROVIDER: S-EPMC11757664 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature