Effects of pulsatile flow on postoperative recovery in adult cardiac surgery with cardiopulmonary bypass: A systematic review and meta-analysis of randomized controlled trials.

ABSTRACT:

Background

The role of pulsatile versus non-pulsatile flow during cardiopulmonary bypass (CPB) is still in debate. This systematic review aimed to comprehensively assess the impact of pulsatile versus non-pulsatile flow on patients' recovery.

Methods

We searched MEDLINE, EMBASE, and Cochrane Library databases for randomized controlled trials comparing pulsatile and non-pulsatile flow in cardiac surgeries with CPB. Data were analyzed using the random-effects model. Then, sensitive analysis and meta-regression were conducted.

Findings

32 studies including 2568 patients were considered in this meta-analysis. There is no difference in in-hospital mortality between the two groups (risk ratio [RR] = 0.74, 95 % confidence interval [CI] = 0.35-1.56, p = 0.43). The ICU stay fo

SUBMITTER: Yan W 

PROVIDER: S-EPMC11758213 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature