Deciphering the Neural Effects of Emotional, Motivational, and Cognitive Challenges on Inhibitory Control Processes.

ABSTRACT: Converging lines of research indicate that inhibitory control is likely to be compromised in contexts that place competing demands on emotional, motivational, and cognitive systems, potentially leading to damaging impulsive behavior. The objective of this study was to identify the neural impact of three challenging contexts that typically compromise self-regulation and weaken impulse control. Participants included 66 healthy adults (M/SD_age = 29.82/10.21 years old, 63.6% female) who were free of psychiatric disorders and psychotropic medication use. Participants completed a set of novel Go/NoGo (GNG) paradigms in the scanner, which manipulated contextual factors to induce (i) aversive emotions, (ii) appetitive drive, or (iii) concurrent working memory load. Voxelwise analysis of

SUBMITTER: Bounoua N 

PROVIDER: S-EPMC11758444 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature