Biases in Volumetric Versus Surface Analyses in Population Receptive Field Mapping.

ABSTRACT: Population receptive field (pRF) mapping is a quantitative functional MRI (fMRI) analysis method that links visual field positions with specific locations in the visual cortex. A common preprocessing step in pRF analyses involves projecting volumetric fMRI data onto the cortical surface, typically leading to upsampling of the data. This process may introduce biases in the resulting pRF parameters. Using publicly available analysis containers, we compared pRF maps generated from the original volumetric with those from upsampled surface data. Our results show substantial increases in pRF coverage in the central visual field of upsampled datasets. These effects were consistent across early visual cortex areas V1-3. Further analysis indicates that this bias is primarily driven by the nonlinear

SUBMITTER: Linhardt D 

PROVIDER: S-EPMC11758450 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature