Short- and Intermediate-Term Morbidity Following Total Pelvic Exenteration in Colorectal Cancer.

ABSTRACT:

Introduction

Total pelvic exenteration (TPE) for clinical T4b colorectal cancer (CRC) is associated with significant morbidity. Short (0-30 days)- and intermediate (31-90 days)-term temporal analysis of complication onset is not well described, yet needed, to better counsel patients considering TPE.

Methods

A retrospective cohort study of consecutive patients with primary or recurrent clinical T4b pelvic CRC undergoing open TPE between 2014 and 2023 was conducted. Clinicopathologic variables were collected for each patient. Postoperative morbidity was classified according to the Clavien-Dindo (CD) grade system and stratified by time of onset within 90 days of surgery. Pearson's Chi-square test, Fisher's Exact test, and the Mann-Whitney U test were used to compare primary vs

SUBMITTER: Guske C 

PROVIDER: S-EPMC11758541 | biostudies-literature | 2025 Jan-Dec

REPOSITORIES: biostudies-literature