All-Cause and Cause-Specific Mortality in Children With Congenital Zika Syndrome in Brazil.

ABSTRACT:

Importance

Congenital Zika syndrome (CZS) can lead to a range of developmental and neurological issues, which increases the risk of early death. However, the all-cause and cause-specific mortality in children with CZS in the first 5 years of life remain unknown.

Objective

To compare the hazard of all-cause and cause-specific mortality before age 5 years among children with and without CZS in Brazil.

Design, setting, and participants

This cohort study used nationwide linked routine data including all children born from January 2015 to December 2018 in Brazil. They were followed-up until age 5 years, death, or December 2020, whichever occurred first. All analysis were conducted in May 2024.

Exposures

Confirmed or probable cases of CZS.

Main outcomes and measur

SUBMITTER: Cardim LL 

PROVIDER: S-EPMC11758593 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature