Clinical Outcomes Through Two Years for Infants With Bronchopulmonary Dysplasia and Tracheomalacia.

ABSTRACT:

Background

Tracheomalacia (TM) is common in infants with bronchopulmonary dysplasia (BPD) and associated with respiratory morbidity. Assessment of TM was historically via bronchoscopy, but recent studies demonstrate that ultrashort echo-time (UTE) magnetic resonance imaging (MRI) can accurately assess TM in neonates.

Research question

Do neonates with MRI-identified TM and BPD have increased respiratory morbidity through age 2 years?

Methods

We performed an observational cohort study of 54 subjects with BPD and assessed TM using UTE MRI at term-equivalent age. TM was defined as an airway minor/major axis ratio (r_d,min) of < 0.7. Outcomes through 2 years of life were evaluated via electronic medical record review.

Results

There were 23 subjects (43%)

SUBMITTER: Zak SM 

PROVIDER: S-EPMC11758772 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature