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Spontaneous Splenic Rupture Leading to the Diagnosis of CML.


ABSTRACT:

Background

Spontaneous splenic rupture (SSR) is a known complication of hematologic malignancy. Rare cases have been reported in which patients presented with SSR prior to diagnosis of chronic myeloid leukemia (CML). We present a case of atraumatic SSR due to CML presenting as persistent abdominal pain.

Case presentation

A 42-year-old man presented with persistent left upper quadrant pain radiating to the lower quadrants ongoing for many months. He additionally had many other systemic symptoms including weight loss, night sweats, dark tarry stools, and progressive fatigue. Initial laboratory tests showed an anemia and a leukocytosis of 170 K/mm3 which uptrended to 230 K/mm3. CT abdomen showed spontaneous splenic rupture without major hemodynamic compromise and was

SUBMITTER: Dahake N 

PROVIDER: S-EPMC11759071 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature