Short-acting beta agonist, antibiotics, oral corticosteroid and association with mortality and cardiopulmonary events in patients with COPD: a retrospective cohort study in Alberta, Canada.

ABSTRACT:

Objective

The purpose of the study was to examine the association between short-acting beta agonist (SABA), antibiotic and oral corticosteroid (OCS) use and mortality and cardiopulmonary outcomes in chronic obstructive pulmonary disease (COPD).

Design

Retrospective cohort study using administrative health data from 1 April 2011 to 31 March 2020.

Setting

Alberta, Canada.

Participants

Patients ≥35 years old with COPD were identified using diagnostic codes.

Primary and secondary outcome measures

Patient characteristics included age, sex, geographical zone and comorbidities (as defined by the Charlson Comorbidity Index). Outcome variables included all-cause and COPD-related mortality. Outcomes were assessed in consecutive 90-day intervals, starting from coho

SUBMITTER: Bhutani M 

PROVIDER: S-EPMC11759206 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature