Efficacy and safety of pharmacological treatments in inclusion body myositis: a systematic review.

ABSTRACT:

Objective

To identify the best evidence on the efficacy of treatment interventions for inclusion body myositis (IBM) and to describe their safety.

Methods

Systematic review of randomised controlled trials (RCTs) of pharmacological treatments of adults with IBM, conducted according to the Cochrane Handbook, updating a previous Cochrane review. The search strategy was run on Cochrane Neuromuscular Disease Group Specialized Register, CENTRAL, MEDLINE and EMBASE, ClinicalTrials.gov and the WHO International Clinical Trials Registry Platform. Assessment of risk of bias, data extraction and synthesis were performed independently by two reviewers. Data pooled in statistical meta-analyses, if possible.

Results

From a total of 487 records, 48 were selected for full-text review

SUBMITTER: Santos EJF 

PROVIDER: S-EPMC11759215 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature