Speckle-illumination spatial frequency domain imaging with a stereo laparoscope for profile-corrected optical property mapping.

ABSTRACT:

Significance

Laparoscopic surgery presents challenges in localizing oncological margins due to poor contrast between healthy and malignant tissues. Optical properties can uniquely identify various tissue types and disease states with high sensitivity and specificity, making it a promising tool for surgical guidance. Although spatial frequency domain imaging (SFDI) effectively measures quantitative optical properties, its deployment in laparoscopy is challenging due to the constrained imaging environment. Thus, there is a need for compact structured illumination techniques to enable accurate, quantitative endogenous contrast in minimally invasive surgery.

Aim

We introduce a compact, two-camera laparoscope that incorporates both active stereo depth estimation and speckle-illum

SUBMITTER: Song AA 

PROVIDER: S-EPMC11759297 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature