Natural Deep Eutectic Solvents as Green Alternatives for Extracting Bioactive Compounds from <i>Sideritis</i> Taxa with Potential Cosmetic Applications.

ABSTRACT: This study investigated the potential of natural deep eutectic solvents (NADESs) for extracting bioactive compounds from the aerial parts of two mountain tea taxa, Sideritis clandestina ssp. peloponnesiaca (Boiss. & Heldr.) Baden and Sideritis raeseri Boiss. & Heldr. ssp. raeseri. Five NADEs, composed of betaine, glycerol, glucose, urea, citric acid, and sucrose, were evaluated for their extraction efficiency compared to conventional solvents (water and 70% ethanol). The total phenolic content (TPC) and antioxidant activity (FRAP and DPPH assays) were determined. Results showed that water was not a good extraction solvent. Despite the great solvent-dependent differences, most NADEs, particularly the betaine-glycerol-glucose mixture (BGG4), exhibited comparable o

SUBMITTER: Zissi L 

PROVIDER: S-EPMC11759769 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature