Association of arterial stiffness and eye disease: a systematic review and meta-analysis.

ABSTRACT:

Background

This systematic review and meta-analysis assesses the association of arterial stiffness with age-related macular degeneration (AMD), glaucoma, retinal vein occlusion (RVO) and retinopathy (diabetic and hypertensive).

Methods

Medline and Embase were systematically searched for observational studies of arterial stiffness and eye disease. Cohort studies were included if they estimated arterial stiffness using any measures based on the arterial waveform, with cross-sectional and case-control studies limited to measures of pulse wave velocity. We assessed the certainty of evidence using Grading of Recommendations, Assessment, Development and Evaluation.

Results

The systematic review of 61 studies (six for AMD, ten for glaucoma, six for RVO and 39 for retinopathy

SUBMITTER: Beros AL 

PROVIDER: S-EPMC11759874 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature