Vaccination coverage and its determinants in patients with multiple sclerosis-a multicenter cross-sectional study.

ABSTRACT:

Background

Complete vaccination coverage is recommended by multiple sclerosis (MS) societies for patients with multiple sclerosis (pwMS) to mitigate infection risks associated with disease-modifying therapies (DMTs).

Objectives

To analyze vaccination coverage and its determinants in pwMS compared to healthy controls, considering vaccination hesitancy, MS-specific vaccination beliefs, trust in information sources, and the role of general practitioners (GPs).

Methods

This cross-sectional multicenter observational study was conducted in six German MS centers. The primary endpoint was a vaccination index (VI) comprising eight standard vaccinations (range 0-1, with higher VI indicating better vaccination coverage). Secondary endpoints included validated measures of general

SUBMITTER: Schade P 

PROVIDER: S-EPMC11760134 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature