Phage therapy in the management of respiratory and pulmonary infections: a systematic review.

ABSTRACT:

Background

Lower respiratory tract infections (LRTIs) pose a significant threat to global health, causing more than 2 million deaths worldwide. This menace is intensified by the alarming increase in drug resistance, which limits the availability of effective antibiotics for bacterial respiratory infections. Consequently, there is an urgent demand for alternative therapeutic options. Phage therapy (PT) has re-emerged as a promising therapeutic approach and as an adjunct to antibiotic treatment.

Objective

This systematic review synthesises the application of PT for LRTIs in humans, providing unified and updated data on the evaluation of the safety and efficacy of PT for LRTIs.

Design

Systematic review.

Data sources and methods

Following the PRISMA guidelines, a c

SUBMITTER: Sarkodie-Addo P 

PROVIDER: S-EPMC11760135 | biostudies-literature | 2025 Jan-Dec

REPOSITORIES: biostudies-literature