Nanospiked Cellulose Gauze That Attracts Bacteria with Biomolecules for Reducing Bacterial Load in Burn Wounds.

ABSTRACT: Nanostructuring surfaces is an emergent strategy to endow materials with abilities to combat pathogenic bacteria. Nevertheless, it remains challenging to create nanospike structures on the curved surfaces of polymer materials, including gauze and other microfibrous medical materials. Additionally, the effects of nanostructured surfaces on bacteria in the presence of proteins and in vivo remain largely unexplored. Herein, we demonstrated the decoration of gauze microfiber surfaces with nanospike structures via the self-assembly of cello-oligosaccharides and investigated the effects of the nanospiked gauze on bacteria in the presence of proteins. The nanospiked gauze had low bacterial adhesion properties in the absence of proteins, whereas in the presence of proteins, it promoted bacterial a

SUBMITTER: Hata Y 

PROVIDER: S-EPMC11760149 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature